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The RAMP System

Response Biomedical
The RAMP® System consists of a portable scanning fluorescence analyzer and single-use, disposable Test Cartridges. This platform technology delivers reliable results in approximately fifteen minutes depending on the assay, and has the potential to
be adapted to more than 250 medical and non-medical tests currently performed in laboratories. Learn more about how the RAMP System works.
 

Patented RAMP Internal Standard

  • Inherent variability is associated with traditional lateral flow assays. Factors contributing to variability include environmental conditions, lot-to-lot membrane variability, system-to-system differences, and sample flow characteristics due to viscosity.
  • RAMP incorporates a quantitative Internal Standard that is run and measured concurrently in every assay to compensate for these variations.
  • The RAMP System consists of two components: a disposable Test Cartridge that houses an analyte-specific immunochromatographic strip, and a portable fluorescence analyzer.
  • The Test Cartridge uses latex particles that are fluorescently labeled and tagged with antibodies against the analyte of interest.
  • Antigen bound particles are captured at the Detection Zone by specific antibodies and a portion of excess particles are captured at the Internal Standard Zone.
  • The Reader measures fluorescence emitted by the complexes captured in the Detection and Internal Standard Zones and calculates a Ratio between these measurements.
  • The RAMP Ratio corrects for inherent variability in the assay.
 
Learn more about RAMP Technology (PDF).
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